Pollen Grains Induce a Rapid and Biphasic Eczematous Immune Response in Atopic Eczema Patients

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Pollen grains induce a rapid and biphasic eczematous immune response in atopic eczema patients.

INTRODUCTION Eczematous reactions to type I allergy-inducing antigens are documented in a subgroup of patients with atopic eczema. Yet, the underlying immunological mechanisms are not well understood. MATERIAL AND METHODS To delineate the effect of native pollen grains on human skin of healthy and atopic individuals we performed patch tests (atopy patch test with native pollen grains, PPT). N...

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ATOPIC DERMATITIS AND ALLERGIC SKIN DISEASE Pollen Grains Induce a Rapid and Biphasic Eczematous Immune Response in Atopic Eczema Patients

METHODS. Individual patients were randomly assigned to undergo prospective HLA-B*5701 screening, with exclusion of previously known HLA-B*5701 positive patients from abacavir treatment, or to undergo a standard approach of abacavir use without screening. All subjects who started abacavir were observed for 6 weeks, the time frame in which a large majority of hypersensitivity reactions occur. The...

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ATOPIC DERMATITIS AND ALLERGIC SKIN DISEASE Pollen Grains Induce a Rapid and Biphasic Eczematous Immune Response in Atopic Eczema Patients

METHODS. Individual patients were randomly assigned to undergo prospective HLA-B*5701 screening, with exclusion of previously known HLA-B*5701 positive patients from abacavir treatment, or to undergo a standard approach of abacavir use without screening. All subjects who started abacavir were observed for 6 weeks, the time frame in which a large majority of hypersensitivity reactions occur. The...

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Eczematous reactions to food in atopic eczema: position paper of the EAACI and GA2LEN.

Food allergy and atopic eczema (AE) may occur in the same patient. Besides typical immediate types of allergic reactions (i.e. noneczematous reactions) which are observed in patients suffering from AE, it is clear that foods, such as cow's milk and hen's eggs, can directly provoke flares of AE, particularly in sensitized infants. In general, inhaled allergens and pollen-related foods are of gre...

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Eczematous reactions to food in atopic eczema: position paper of the EAACI and GALEN

Food has been discussed as a trigger factor of atopic eczema (AE; atopic dermatitis) for many years. Many patients suppose that allergic reactions to foods cause – at least in part – eczema. During the course of the disease, a majority of the patients try elimination diets (1) which can cause malnutrition and emotional stress especially in children. Most clinicians and investigators believe tha...

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ژورنال

عنوان ژورنال: International Archives of Allergy and Immunology

سال: 2007

ISSN: 1018-2438,1423-0097

DOI: 10.1159/000109290